Understanding COVID-19 Vaccines
Introduction
The development of COVID-19 vaccines offers hope for the future amidst the pandemic. Let's explore the key aspects of three prominent vaccines: Pfizer, Oxford AstraZeneca, and Moderna.
Vaccine Mechanisms
The vaccines work differently:
- Pfizer and Moderna: Contain mRNA, which prompts the body's immune response.
- Oxford AstraZeneca: Utilizes the spike protein of the coronavirus, incorporated into an adenovirus vector.
Immune Response
Upon vaccination:
- Immune Activation: The immune system generates defensive cells, including memory cells, providing long-term protection.
- Memory Cells: Offer lifelong immunity by recognizing and swiftly responding to future encounters with the virus.
Vaccine Storage and Administration
Proper storage and administration are crucial:
- Pfizer: Stored at -70°C initially, then at 2-8°C for up to 5 days after thawing.
- Oxford AstraZeneca: Stored at 2-8°C for varying durations, depending on whether the vial is opened or unopened.
- Moderna: Arrives frozen and should be stored at 2-8°C after thawing.
- Administration: Given intramuscularly, typically in the deltoid muscle of the arm.
Consult with your doctor to understand the benefits and risks associated with COVID-19 vaccination or boosters.